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American Association for Cancer Research, AACR, Journals, journal, articles, papers, publications, manuscript, submit, submission system, SmartSubmit, Impact Factor, cited, citations, OnlineFirst, published ahead of print, Author Services Center, High-Impact Science, CCR Focus Archive, Centennial Series Reviews, Meeting Abstracts Online, CR Magazine, Meeting Reports, AACR Education Book, Cancer Medicine 8, Information for Author, Editors, Reviewers, Readers, Subscribers, Librarians, Advertisers, Cancer Research, CanRes, Clinical Cancer Research, CCR, Cancer Epidemiology, Biomarkers & Prevention, CEBP, Molecular Cancer Research, MCR, Molecular Cancer Therapeutics, MCT, Cancer Prevention Research, CaPR, Cancer Discovery, New Issue CCR Focus DNA Repair, Our growing understanding of the mutational complexity of most solid tumors makes it clear that DNA will remain among the most important therapeutic targets for the foreseeable future. That point has been reinforced in recent months by clinical data showing activity of PARP inhibitors in breast cancer in patients who have loss of BRCA1, an important gene in homologous recombination, a double-strand break DNA repair pathway. The CCR Focus section in the September 15th issue of Clinical Cancer Research is aimed at increasing our comprehension of some of the more translational aspects of DNA repair. Read more about other topics by visiting the CCR Focus Archives.

The mission of the AACR is to prevent and cure cancer through research, education, communication and collaboration. The membership includes 32,000 basic, translational and clinical researchers; health care professionals; and cancer survivors and advocates. The American Association for Cancer Research accelerates progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants, research fellowships and career development awards. The AACR publishes six major peer-reviewed journals and CR, a magazine for cancer survivors and their families, patient advocates, physicians and scientists.